Ronald A. Bergman, Ph.D., Adel K. Afifi, M.D., Paul M. Heidger,
Jr., Ph.D.
Peer Review Status: Externally Peer Reviewed
Human, Helly's fluid, Mallory-Azan stain, 162 x.
White pulp: A mass of compact lymphatic tissue filled with lymphocytes surrounding the central artery.
Central artery: A misnomer, as it is invariably eccentrically placed in the white pulp. A branch of the splenic artery, it gives off numerous capillaries before leaving the white pulp to enter the red pulp.
Red pulp: So-called because of its color during life. Red color is imparted by the abundant erythrocytes. Lymphatic tissue of the red pulp is not as compact as that of the white pulp with which it blends. Apparent compactness in fixed preparations is attributed to the collapse of sinusoids after death.
Trabecula: Collagenous connective tissue projection from the capsule. Branches repeatedly, and imperfectly divides the spleen into anastomosing chambers.
Arteriole: Terminal branches of the central artery in the red pulp. It has no investment of compact lymphatic tissue.
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