Plate 15.296 Pineal Gland
Ronald A. Bergman, Ph.D., Adel K. Afifi, M.D., Paul M. Heidger,
Jr., Ph.D.
Peer Review Status: Externally Peer Reviewed
Human, 10% formalin, H. & E., 162 x.
The pineal gland is made up of plates of cells separated by septa. Two cell types are recognized by special techniques, the more common parenchymal cell and the neuroglial (astrocyte-like) supporting cell. The latter is found between clusters of parenchymal cells. The two cell types cannot be distinguished in ordinary H. & E. preparations. Concretions or brain sand characterize the pineal gland and increase with age. They have a mineralized organic matrix and, at high magnification, appear lamellated.
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