A. Non-keratinized B. Keratinized
Ronald A. Bergman, Ph.D., Adel K. Afifi, M.D., Paul M. Heidger,
Jr., Ph.D.
Peer Review Status: Externally Peer Reviewed
A. Human, 10% formalin, H. & E., 162 x.
B. Human, glutaraldehyde-osmium fixation, toluldine blue stain, 612
x.
Stratified squamous epithelium is made up of several layers of cells. The deepest layer is composed of cuboidal or low columnar cells, the middle layer of polygonal cells, and the superficial layers of flattened cells. The epithelium caps connective tissue papillae (lamina propria or dermis). The stratified squamous epithelium located internally (esophagus) is non-keratinized, whereas that located externally (skin) is keratinized (i.e., possesses a stratum corneum). The stratum corneum is made up of flattened non-viable, non-nucleated epithelial cells containing keratin. (See also Plate 135.)
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